England defender Michael Dawson has been ruled out of Tuesday's Euro 2012 qualifier in Switzerland after suffering an injury against Bulgaria.
The Tottenham centre-half appeared to hurt his knee in the second half of England's 4-0 Wembley win on Friday and has been sent back to his club.
The 26-year-old was stretchered off in apparent agony before the hour mark.
He had an initial examination on Saturday morning and England have decided not to call up a replacement.
That could mean a recall for West Ham defender Matthew Upson alongside Phil Jagielka, though Bolton stopper Gary Cahill acquitted himself well on his international debut after coming off the bench to replace Dawson for the final half an hour against Bulgaria.
Cahill was the first Bolton player to represent England since Michael Ricketts in February 2002 while Jagielka was winning only his fifth cap so Capello could choose to use Upson's experience alongside the Everton man in Basel.
The West Ham captain was left out of both the Bulgaria game and last month's friendly victory over Hungary although he played against both Slovenia and Germany in the World Cup finals in the summer.
First-choice pairing John Terry and Rio Ferdinand are out of the reckoning with hamstring and knee problems respectively.
Dawson's injury is worrying news for Spurs with the transfer window closed and the north Londoners facing their first Champions League group match on 14 September against Werder Bremen.
The injury took the shine off an otherwise impressive opening to England's Euro 2012 qualifying campaign.
Jermain Defoe's hat-trick combined with a first goal for England for Adam Johnson saw the hosts run out comfortable winners at Wembley to start the rebuilding process after their World Cup failure on a positive note.
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