Nani was replaced in the first half of the Champions League match
Manchester United's 3-0 Champions League win over Bursaspor came at a cost because winger Nani and midfielder Darren Fletcher both suffered injuries.
Nani limped off with a groin problem and will miss Saturday's Premier League game against Wolves, while Fletcher, who scored the opener, hurt an ankle.
"Nani has a groin injury and is out for Saturday and I think Darren will be out as well," said boss Sir Alex Ferguson.
"That part has been disappointing but these things happen in football."
Nani was replaced by Park Ji-Sung in the 29th minute but Fletcher lasted long enough to find the net just after half-time.
United are also without strikers Michael Owen and Wayne Rooney at the moment because of hamstring and ankle injuries respectively.
Plus defender Rio Ferdinand, who returned to the Red Devils side in September after injuring a knee when in World Cup training with England in June, missed the trip to Turkey.
"We may have Darron Gibson back after a bout of flu but Anderson has had a virus as well and I don't think he will be ready," added Ferguson.
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